New England Hematology/Oncology Associates, along with Newton-Wellesley Hospital’s Clinical Research Team, offers patients access to a variety of clinical trials of promising new therapies. Review the list below to find open protocols and consider referring your patients. The Cancer and Leukemia Group B (CALGB) is a national clinical research group.
As a clinical trials affiliate and CALGB affiliate of Dana-Farber/Partners CancerCare, Newton-Wellesley Hospital participates directly in DF/PCC-led clinical research. This allows our patients to have access to many of the same studies being conducted at Boston’s premier cancer research hospitals.
The network has made it possible for hundreds of cancer patients to enroll in clinical trials. People who had difficulty participating in trials because they lived far from Boston now have access to some of the latest investigational therapies at a hospital near them. Last year, the affiliates enrolled 160 patients in DF/PCC-sponsored trials and CALGB trials combined.
To learn more about eligibility and participation contact a member of the clinical research team.
Newton-Wellesley Hospital Office of Research Manager: Hope Violette, RPh, CIP | Phone: 617-243-6493 | Email
Newton-Wellesley Hospital Oncology Research Nurse: Kara Malcolm, RN | Phone: 617-243-5089 | Email
Newton-Wellesley Hospital Oncology Research Coordinator: Judy Chow | Phone: 617-243-6392 | Email
Medical Director of Oncology Research: Caroline Block, MD | Phone: 617-658-6000| Email
Breast Cancer
CALGB 40502 (Breast – Metastatic 1st Line)
Randomized phase III trial of weekly paclitaxel compared to weekly nanoparticle albumin bound nab-paclitaxel Phase III or ixabepilone, all combined with bevacizumab, as first -line therapy for locally recurrent or metastatic breast cancer. DF# 08-360. More Info…
CALGB 40601 (Breast – HER2-positive Neoadjuvant)
Randomized Phase III Trial Of Paclitaxel Combined With Trastuzumab, Lapatinib, Or Both As Neoadjuvant Treatment Phase III Of Her2-Positive Primary Breast Cancer. DF# 08-370 More Info…
370CALGB 40603 (Breast – Triple Negative Neoadjuvant)
Randomized Phase II 2 X 2 Factorial Trial Of The Addition Of Carboplatin +/- Bevacizumab To Neoadjuvant Weekly Phase II Paclitaxel Followed By Dose dense AC In Hormone Receptor-Poor/Her2-Negative Resectable Breast Cancer. DF# 09-260. More Info…
DF 94-138 (Breast, Ovarian – Banking/Registry) Genetics and Other Causes of Cancer
The REACH project collects risk factor information, blood and tissue specimens from patients and family members at high risk for breast and/or ovarian cancer. The data and specimen bank will be used as a resource to be shared with researchers working in the areas of breast and ovarian cancer risk, prevention and treatment. DF# 94-138
GI Cancer
CALGB 80405 (Colon – Metastatic)
A Phase III Trial of Irinotecan / 5-FU / Leucovorin or Oxaliplatin / 5-FU / Leucovorin with Bevacizumab, or Cetuximab Phase III (C225) for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum. DF# 05-449 More Info…
Lung Cancer
CALGB 30704 (NSCLC – 2nd Line treatment)
A Randomized Phase II Study To Assess The Efficacy Of Pemetrexed Or Sunitinib Or Pemetrexed Plus Sunitinib In Phase II The Second-Line Treatment Of Advanced Non-Small Cell Lung Cancer. DF# 08-144 More Info…
Lymphoma
CALGB 50501 (Lymphoma – Treatment)
A Phase II Trial Of Bortezomib and Lenalidomide For Relapsed or Refractory Mantle Cell Lymphoma DF# 08-066 More Info…
Click below to see more information about the active clinical trials:
Oncology Research Summer Newsletter 2010
Oncology Research Winter Newsletter 2010
Oncology Research Spring 2011